Man 69 yo,  pain  at 
epigastric area, no  fever,  no GI tract trouble.
Abdominal  ultrasound  detected 
abnormal  gallbladder: thickening
of the wall with one  mass  at gall bladder  fundus 
invasion to liver, suggestion of gallbladder abscess ( see 4 ultrasound pictures).
Blood test  are normal:   WBC  not rising, CA 19-9  normal
MRI with CE gado  showed this mass  in  high 
enhancement  invasion in to  liver and 
transverse colon, the  biliary
system was  normal.
With  this clinical
situation and blood tests, US first
and  MRI,  what is your diagnosis ?
Microscopic with imunohistostaining is leiomyosarcoma of the gallbladder..it is very rare  case in the word  had been published.
DISCUSSION: this case  had no  clinical signs of acute  cholecystisis, no stone 
in gallbladder; ultrasound  showed
 the 
wall of  the gallbladder   perforated and 
adherent , invading  liver  tissue, this mass was  hypovascular  in protruding  into lumen of gallbladder as a tumor and  going to extra wall of gallbladder.
Open operation 
with  diagnosis  of 
tumor of gall bladder (surgeon  removed  gallbladder  and 
resection one part of liver  and  great omentum).  Specimen was 
hard and necrosis.
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