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Wednesday, 20 April 2016

CASE 374: MALIGNANT PHEOCHROMOCYTOMA and CUSHING SYNDROME, Dr LÊ TUẤN KHUÊ, Dr NGUYỄN MINH THIỀN, Dr PHẠM THẾ ANH, Dr PHAN THANH HẢI, MEDIC MEDICAL CETER, HCMC, VIETNAM


Woman, 20 yo, discovered HTA  in pregnant at 16 weeks
 5-months before this hospitalization: pregnant  in 28ws, sudden obstetrical  seizures in Ca Mau hospital.  Diagnosis of eclampsia / hypertension / 28w pregnant. Treatment: cesarean section.
 After surgery , patients changed  body shape, round, fat face, neck, stretching skin, increasing weight gain, examination findings adrenal gland tumor  in Can Tho General Hospital, then transferred to Binh Dan hospital.
In clinic examination, obesity, Cushing syndrome,  other organs detect no abnormalities. HTA being treated.


Blood and urine catecholamine increasing, blood and urine cortisol increasing, ACTH reducing.





MSCT: right adrenal tumor.

CONCLUSION=  Female patient 20 yo, hospitalized for weight gain and  HTA, Cushing syndrome. Reducing of  blood ACTH and metanephrine; catecholamine and cortisol secretion increasing in blood, and urine.
Surgery removed right adrenal tumor. Pathological result is malignant pheochromocytoma.




 Secreted adrenal neoplasms - suppression of axis of  adrenal pituitary.

1 comment :

Hong Anh said...

Post-op test to measure adrenal and pituitary hormones should be done.